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March 31, 2008

Type 2 Diabetes: Living With Complications - Medications

Filed under: Uncategorized — waterman9 @ 3:47 pm

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Erectile dysfunction pill
. You may be taking insulin by
injection or through an
insulin pump alone or along with oral diabetes
medication. Taking these medications as prescribed can help keep your blood
sugar levels within your
target range. For information on these medications,
see the Medications section of the topic
Type 2 Diabetes: Living With the Disease.

You may need to take:

  • Aspirin. If you are age 30 or older, talk to
    your health professional about taking a low-dose, or baby, aspirin daily to
    prevent
    heart attack,
    stroke, or other large blood vessel disease (macrovascular disease).1
  • An angiotensin-converting enzyme (ACE) inhibitor,
    angiotensin II receptor blocker, or other medication if you have
    high blood pressure or have protein in your urine.
    These medications can slow or prevent further damage to your
    kidneys.
  • Medications for digestive problems. The type of medication
    will depend on the problem you are having. For example, if you have
    gastroparesis, you may take metoclopramide (Reglan),
    domperidone (available in Europe and Canada), or
    erythromycin.
  • Nonerectile dysfunction tablets
    pain relievers, creams, or
    prescription oral or injection medications if you have pain from
    peripheral neuropathy.
  • Viagra, Levitra, or
    Cialis if you have erection problems. These medications can aggravate heart
    problems in some people, especially those taking nitrate medications (such as
    nitroglycerin). Check with your doctor before taking any of these
    medications.

Medication Choices

Medications for some complications include:

  • Aspirin after a
    heart attack or stroke or to prevent these.
  • Statins such as atorvastatin (Lipitor), simvastatin
    (Zocor), or pravastatin (Pravachol), to help prevent heart attack or
    stroke.
  • Angiotensin-converting enzyme (ACE) inhibitors or
    angiotensin II receptor blockers (ARBs) for diabetic
    nephropathy.
  • Phosphodiesterase-5 inhibitors (PDE-5
    inhibitors), such as Viagra, Levitra, or Cialis if you have erection
    problems. Check with your doctor before taking any of these medications.

What to Think About

Keep your blood sugar levels tightly within a normal or
near-normal range by taking your oral diabetes medication (and, in some cases,
insulin) as prescribed.

If you have
high cholesterol, take erectile dysfunction tablets

medications (such as statins) to keep your
LDL cholesterol level less than 100 mg/dL (2.60
mmol/L), your
buy online soft tab viagra
level less than 150 mg/dL (1.7 mmol/L),
and if possible, your
HDL cholesterol level more than 40 mg/dL (1.15 mmol/L)
in men. Women may need an HDL level of more than 50 mg/dL.7 See the topic
High Cholesterol.

If you have high blood pressure, take medications to keep your
blood pressure consistently below 130/80 mm Hg. If your
systolic blood pressure is between 130 mm Hg and 139
mm Hg or your
diastolic blood pressure is between 80 mm Hg and 89 mm
Hg, you may try some lifestyle or behavioral therapy for 3 months before
starting medication.6 For more information, see the
topic
High Blood Pressure (Hypertension).

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March 30, 2008

Prostate Cancer: Glossary

Filed under: Uncategorized — waterman9 @ 3:37 pm

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You may hear a number of words you are not ed medicine
with during prostate
cancer diagnosis, treatment, and recovery. Some definitions follow. Just click
on a letter to find a specific word, or scroll avoid generic viagra
the entire list.

A
B
C
D
E
F
G
H
I
L
M
N
O
P
R
S
T
U
V
W
X

impotence.

The Cleveland Cheapest generic substitute viagra

Urological Institute.

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March 29, 2008

Happy, Healthy, and Hard

Filed under: Uncategorized — waterman9 @ 2:45 pm

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As the saying goes, the best measure of a man’s character is the company he
keeps. But what about his health? According to Steven Lamm, MD, the best
measure of that is his erect penis.

“There’s an incredibly important link between a man’s health and sexual
performance,” Lamm, an assistant professor of medicine at New York
Erectile dysfunction treatment
, tells WebMD.

Lamm’s recent book, The Hardness Factor, is a flashing neon sign
pointing to that link.

It is well known that heart disease, as well as diabetes, depression,
obesity, substance abuse, and many other health problems can quash erections.
Getting an erection isn’t crude mechanics, like inflating a balloon. It’s a
complex process in which blood vessels, muscles, hormones, the nervous system,
and the psyche all work together. If one part isn’t working well, it affects
the whole apparatus.

This isn’t another book touting Viagra, like Lamm’s The Virility
Solution
, published in 1998, the same year Viagra hit the market. Lamm
says The Hardness Factor is not for men who are already dealing with
erectile dysfunction (ED). His aim is to convince young, healthy men to take
better care of themselves by speaking to their penises.

“If you want a 28-year-old man to stop smoking, let him read the
book,” Lamm says.

Heart Health and Sexual Health

Others in the field of sexual medicine agree that erectile function can be
closely related to overall health, viagra vs cialis
heart health.

“When men who are otherwise healthy ask what they can do to prevent ED,
certainly the very things we recommend for cardiovascular fitness are exactly
the same things they should be doing,” Drogo Montague, MD, a urologist at
the Cleveland Clinic, tells WebMD.

To get erect, the penis must become engorged with blood. Atherosclerosis, a
condition in which fatty deposits build up inside arteries, may restrict blood
flow to the penis and cause erection difficulties. Diets high in fat and
cholesterol, high blood pressure, obesity, diabetes, and smoking are the main
causes of atherosclerosis.

“It’s very appealing to say that if you don’t have those unhealthy
factors in your lifestyle, then you’re less likely to develop erectile
dysfunction,” says Ira Sharlip, MD, a urologist at the University of
California, San Francisco.

“There are pretty strong suggestions that those things are true,” he
tells WebMD.

One persuasive piece of evidence appeared in the April 2004 issue of the
Journal of the American College of Erectile dysfunction pill
. Between 1972 and 1974,
researchers in California surveyed 1,810 men about their risks for heart
disease. In 1998, researchers contacted 844 of them who were still alive and
asked them about their erectile function. The men who had risk factors for
heart disease in the ’70s were much more likely to have ED 25 years later.

If men with heart disease are more likely to develop ED, it stands to reason
that having ED could be a warning sign for heart disease, too.

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March 28, 2008

A Woman’s Guide to Reviving Sex Drive

Filed under: Uncategorized — waterman9 @ 2:31 pm

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Has the “free love” generation lost its mojo?

If you talk to baby boomer gals, it seems the answer is yes. Indeed, as
millions of women enter perimenopause and then
transgress to menopause and beyond,
many say they check their sex drive at the door and most are not happy about
it.

“I don’t think a day goes by when at least one patient and usually
more complain that their sex drive is dropping off and want to know what they
can do about it,” says Laura Corio, MD, a levitra vs viagra
and clinical
instructor at Mt. Sinai Medical Center in New York City.

Clinically known as HSDD (hypoactive sexual desire disorder) Corio says she
doesn’t think more women are affected now than in the past, but she does
believe more are coming forward — prompted, at least in part, by the success
male potency drugs like Viagra.

“The man gets a prescription for Viagra and he’s ready to rock and roll
while she’s thinking ‘Hey, where’s my pill?’ If she’s not ready to jump in the
old van and join him for a ride, there can be real problems,” says
Corio.

Discovering What’s Wrong

While male sex drive is easy to define — and relatively easy to restore –
that’s often not the case for women. Because the female sex drive is
multifactorial, the desire to make love is not only influenced by physical
issues, but emotional ones as well.

“Part of the desire to make love is clearly physical, but part is also
emotional depression can make a
difference, so can any emotional issue in a woman’s life; female sex drive is
very multidimensional,” says Glenn D. Braunstein, MD, an endocrinologist
and chair of the department of medicine at Cedars Sinai Medical Center in Los
Angeles.

While emotions are frequently behind a loss of sex drive in younger women,
doctors say it is frequently the agingprocess itself that’s at
when desire changes in women over age 45.

“The very fact that a woman is no longer ovulating regularly, or not
ovulating at all, automatically takes her sex drive down a few notches,”
says Steven Goldstein, MD, professor of ob-gyn and NYU Medical Center in New
York City.

Nature’s Design for Sex

Indeed, as many women are aware, Mother Nature built in a natural increase
in the desire for sex beginning just prior to ovulation, and lasting several
days afterwards — not coincidentally, the only time of the month conception is
possible.

Stop ovulating, says Goldstein, and you automatically lose that regularly
scheduled boost in your sex drive that has been present since puberty — and
you’re probably going to notice.

“There’s nothing wrong with you; it’s just the way nature works,”
says Goldstein.

Moreover, around menopause, when there
is also less estrogen circulating in your body, that too can bring your sex
drive down for the count.

“Estrogen is a mood elevator, it works in the brain to maintain interest
in sex, but it also works at the level of the genitals, helping to increase
sensation and just making sex more erectile pill,” says Corio.

Without it, she says, not only can desire take a dive, vaginal tissue begins
to dry and shrink. As a result, intercourse can become dysfunction pill
, or even
painful. Problems with desire, say experts, are easy to erectile dysfunction
.

“Who wants to make love when making love hurts?” asks Goldstein.

Moreover, he says, avoiding sex because of pain only leads to more pain. The
old “use or lose it” theory really does apply.

“From a strictly physical standpoint, the less sex you have the more
painful it is when you try to have it,” he says.

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March 27, 2008

Clinical Trials About ED

Filed under: Uncategorized — waterman9 @ 2:19 pm

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There are currently several clinical trials under way for treating erectile
dysfunction erectile pill
(ED) caused by prostate cancer.

Trial 1

In this trial, the over the counter erectile dysfunction drug of nerve-sparing prostatectomy (surgical
removal of the entire prostate while preserving the comparison levitra viagra

nerves), with and without nerve grafting, followed by standard therapy is being
examined. Participants will be in one of two groups: the first group will have
nerve-sparing prostatectomy with nerve grafting, then will use a standard
therapy such as Viagra, a vacuum constriction device, injection therapy, or
MUSE (suppository in urethra for erections) therapy. Participants in the second
group will have the nerve-sparing surgery without nerve grafting, and will use
the same standard therapy as the first group. The objectives of the study are
to compare the two types of surgery for effectiveness and their effects on
potency rates and erection quality in men with prostate cancer.

Trial 2

This study will be evaluating the effectiveness of Prograf, a medication
known to suppress the immune system, in the prevention of erectile dysfunction
in men who have had a nerve-sparing prostatectomy. Participants will be in one
of two groups: the first group will receive the active medication and the
second group will be given a placebo (sugar pill). The study will look at the
percentage of people who can achieve spontaneous erectile function.

Trial 3

In the third trial, researchers are examining the effectiveness of erectile
dysfunction treatment with Viagra versus a placebo for men with prostate cancer
who have undergone radiation therapy and total androgen suppression. The
studies are attempting to determine if there is a difference in overall sexual
function and cialis vs viagra
between Viagra and placebo.

Trial 4

This study will be looking at the effects of radiation therapy, high energy
X-rays to destroy cancer cells, on erectile dysfunction. It will compare generic viagra prices

whether reducing the dose of radiation helps to prevent ED. Participants will
be placed into one of two groups: the first one will receive the standard
radiation therapy while the second one will receive a restricted dose of
radiation.

Reviewed by the doctors at the Glickman Urological
Institute at The Cleveland Clinic.

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March 26, 2008

Erection Problems (Erectile Dysfunction) - Medications

Filed under: Uncategorized — waterman9 @ 2:06 pm

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erection problems (erectile dysfunction) that are
caused by blood vessel (vascular), hormonal, nervous system, or pills

problems. They also may be used along with counseling to treat erection
problems that have psychological causes.

If erection problems could be caused by a
prescribed medication, it may be possible to change
the dose or try another medication. Do not change or stop taking any medication
without first talking with your health discount generic levitra online viagra
.

Medication Choices

Commonly used oral medications include:

  • Phosphodiesterase-5 inhibitors (PDE-5
    inhibitors) such as Viagra, Levitra, and Cialis.

Other medications that may be used include:

  • Injected medications.
  • Intraurethral alprostadil (MUSE).

Hormones and other medications may be prescribed for
men who have low
testosterone or high
prolactin levels.

Some men have tried
yohimbine-a prescription medication that should not be
confused with the dietary supplement yohimbe-to treat erection problems.

For more information on medication choices, see:

Should I use levitra womans
5 inhibitors
(such as Viagra, Levitra, or Cialis) for erection
problems?

Should I use injections for erection
problems?

What To Think About

PDE-5 inhibitors and heart problems

Health experts have debated the use of PDE-5 inhibitors in men
with heart disease, because deaths have been reported after use of Viagra. The
1999 American College of Cardiology/American Heart Association (ACC/AHA) Expert
Consensus Document noted that PDE-5 inhibitors may be dangerous for people
who:3

  • Have
    coronary artery disease (CAD).
  • Have
    heart failure and low blood pressure.
  • Are
    taking many different drugs for
    high blood pressure.

However, several more recent studies have reported that some
men with heart problems may be able to take PDE-5 inhibitors safely. Talk to
your health professional about whether PDE-5 inhibitors are appropriate for
you.

  • One study found no evidence of increased
    risk for
    heart attack or CAD in men who use Viagra.4
  • Another study in men with CAD reported that
    Viagra does not lead to heart attack and that heart attacks and other
    keyword order viagra
    problems reported after taking Viagra may be related more to the
    physical activity of intercourse than to the medication.5
  • A study of 35 men found that Viagra is safe for
    men with moderate heart failure.6

Sexual activity is exercise. If you have a heart condition and
have not been sexually active for a while, talk with your health professional
to make sure you can engage in sexual activity safely.

PDE-5 inhibitors should never be used if
you may need to take a
nitrate-containing medication, such as nitroglycerin.
Taking nitroglycerin and a PDE-5 inhibitor within 24 hours of each other may
greatly lower your blood pressure, which could lead to a heart attack,
stroke, or death.

If you are taking a PDE-5 inhibitor and are going to have a test
for heart disease, be certain your doctor knows you are taking it. You should
not take a PDE-5 inhibitor for 24 hours before the test. If you develop a
problem during the test, nitrate-containing medications such as nitroglycerin
may be used.

Although oral medications for erection problems can be purchased over the Internet, you should still talk with your health professional before using this medication. This is especially important if you have a heart problem.

If you are using a combination of drugs for high blood pressure,
PDE-5 inhibitors could result in low blood pressure (hypotension). Also for
this reason, you should not take alpha cheapest generic price viagra
to lower blood pressure
and to treat an enlarged prostate-with these medications without talking to
your health professional; the combination could cause a dangerous drop in blood
pressure.

Although the antidepressant medication trazodone has been used
for treating erection problems, there is no current evidence that it is
effective for this purpose.1

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March 19, 2008

ED Drugs May Treat Urinary Problems

Filed under: Uncategorized — waterman9 @ 8:19 am

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May 22, 2007 — Medications commonly used to treat erection problems in men
may also relieve the bothersome urinary symptoms associated with an enlarged
prostate gland, researchers say.

Studies on the topic were presented this week at the annual meeting of the
American Urological Association in Anaheim, Calif.

“Before, we looked at these two conditions as two different
diseases,” says Kevin McVary, MD, professor of urology at Northwestern
University Feinberg School of Medicine in Chicago, who moderated a press
briefing.

But in the past three or four years, he says, the thinking among urologists
has changed.

Sexual performance in men seems to decline as their prostate enlargement
becomes more severe, experts have begun to notice. Doctors also notice
that men with milder prostate problems often have less erectile dysfunction
(ED) than do those with moderate or severely enlarged prostates and urinary
symptoms.

“These two diseases — erectile dysfunction and the lower urinary tract
symptoms associated with benign prostatic erectile dysfunction drugs
— are probably
linked,” McVary says.

Conditions Increase With Age

Prostate problems and ED problems both tend to increase with age. About 31%
of men aged 50 to 59 have an enlarged prostate (also known as benign prostatic
hyperplasia or BPH); 44% of those 70 and older have an enlarged prostate,
according to the National Institutes of Health. As the gland enlarges, it
constricts the urine-carrying tube called the urethra, making it difficult to
empty the bladder.

Common symptoms of BPH include weak urine stream, leaking or dribbling,
feeling that the bladder hasn’t emptied completely after voiding, and more
frequent urination.

Medications are prescribed to relieve the symptoms. Some medications work by
relaxing the muscles at the neck of the bladder and prostate; others inhibit a
hormone that contributes to the growth of the gland.

Erectile dysfunction, defined as an inability to get or keep an erection, is
experienced by 20% to 46% of men aged 40 to 69, according to the NIH.
Medications to treat erection problems help increase blood flow to the penis
when a man is sexually stimulated.

Cialis Study

A once-a-day dose of Cialis helped men with erectile dysfunction and
moderate to severe urinary tract symptoms due to an enlarged prostate improve
sexual erectile dysfunction drugs, says Marc Gittelman, MD, a urologist in Aventura, Fla., and
a study researcher.

Of the 281 men who enrolled in the study, “81% were sexually active, and
they were in their low 60s,” he says. All had moderate to severely enlarged
prostates and urinary problems; 68% of the sexually active men had a medical
history of erectile dysfunction. Gittelman’s team assigned about half to take
placebo and half to take Cialis.

At the end of 12 weeks, men who took Cialis — first 5 milligrams a day and
then up to 20 milligrams — had cheapest citrate sildenafil higher scores on a standard index
of erectile function, he says.

He especially wanted to see if they were as likely to do well if their
urinary problems were severe as opposed to moderate. “They are equally
statistically likely to respond to a dose of Cialis,” he says.

The study was funded by Lilly, which is the maker of Cialis.

In another study, 223 men aged 45 to 64 who had urinary symptoms due to an
enlarged prostate were assigned either to a group given 10 milligrams of
Levitra twice daily for eight weeks or a placebo for the same time period.

Compared with placebo, treatment with the ED drug significantly improved the
men’s quality-of- life scores and their reports of urinary obstruction and
irritation, says Boris Schlenker, MD, a urologist at
Erectile dysfunction advices
Hospital in Munich, Germany, who presented the
data. Erectile function improved in those who took the ED drug.

“Levitra is a promising new drug for men with lower urinary tract
symptoms, but we need long-term data on how it might affect the progression of
the disease,” he says.

The Viagra Study

In a third study, McVary assigned 369 men aged 45 and up who had both
erectile dysfunction and lower urinary tract symptoms to take either 50
milligrams of Viagra every night, 50 milligrams of Viagra an hour before
planned sexual activity, or to take a placebo. The dose increased to 100
milligrams after two weeks.

When he evaluated their erectile function and urinary symptoms, he found 73%
of the men with severe symptoms improved to having mild or moderate symptoms at
the end of the study.

“The changes in prostate symptom scores were dramatic,” he says.
“They compete with alpha blockers.” Alpha blockers are one type of drug
commonly prescribed to treat urinary symptoms associated with an enlarged
prostate. The more severe the urinary symptoms, the greater the
relief, he says.

The study was funded by Pfizer, which is the maker of Viagra.

“This really is erectile pill
,” says Gittelman.

The experts aren’t sure if the ED drugs will eventually supplement or
replace drugs used for urinary problems associated with an enlarged prostate,
or if new formulations might be developed to deal with both conditions.

Some men on the ED drugs did report side effects, says Schlenker, with the
most common in his study being headache.

It’s not known exactly why the ED drugs also help the urinary symptoms,
McVary says. By increasing blood flow to the pelvic area, the ED drugs may help
relax the bladder enough to relieve the urinary problems.

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March 18, 2008

Sexual Problems in Women - Medications

Filed under: Uncategorized — waterman9 @ 7:08 pm

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sexual problems are often complex and interrelated.
Medications may be used in treating certain conditions that contribute to
sexual problems.

Medication Choices

Estrogen. If you only have vaginal
dryness and irritation (and not other symptoms such as hot flashes), you can
use a limited amount of
estrogen in a cream, tablet, or ring in the vagina.
The daily estrogen makes your tissue less thin and sensitive and more moist.
Many women find that using a cream or tablet twice a week is enough. This may
increase vaginal tone and lubrication, which will decrease
vulvar dryness, irritation, and shrinkage (atrophy).

If you also have other
menopausal symptoms that affect physical and mental
well-being, talk to your health erectile dysfunction remedy
about taking daily (systemic)
estrogen therapy.
Estrogen can increase the blood flow in the
vagina, as well as reduce hot flashes and other
symptoms of
menopause.
Estrogen therapy or
estrogen-progestin therapy can be oral (pills),
vaginal, or transdermal (with a patch). In a small number of women, hormone
therapy causes heart disease, breast cancer, dangerous blood clots, stroke, and
dementia. Talk to your health professional about whether this therapy is right
for you.

Woman use viagra
.
This hormone may play a part
in a woman’s sex drive and satisfaction. The ovaries make
cialis strong viagra vs
throughout a woman’s lifetime. Women have
the most testosterone in early adulthood; testosterone levels drop by half
between the early 20s and the early 40s.

In women who have their ovaries removed (oophorectomy),
testosterone drops by 50%.10 If you have had an
oophorectomy, your health professional may suggest trying
testosterone therapy. But the U.S. Food and Drug
Administration (FDA) has not approved any testosterone therapy for women.

What To Think About

The methyltestosterone-estrogen formula called Estratest is
not approved by the FDA. The company that makes it
markets it for moderate to severe
menopausal symptoms. It is also prescribed to some
menopausal women to improve sexual desire and
response. But Estratest is made with
methyltestosterone, which the body uses differently than testosterone. It does
not directly raise the amount of testosterone in your body. And, taking a
testosterone by mouth does put you at risk for problems with your liver and
possibly your heart. Using a patch or cream does not.

At this time, there is no testosterone pill, patch, or cream
approved for women-those made for men have too high a dose for women. Side
effects of too much testosterone include acne, facial hair, and loss of hair
and a deepening of the voice, which may be permanent.

No studies have looked at the benefits and risks of taking
testosterone for longer than 6 months. The long-term effects of testosterone
therapy in women are not known.10

Sildenafil (Viagra) is used to treat
erectile erectile dysfunction treatment
in men. The maker of this
medicine has decided not to market it for improving women’s sexual desire and
arousal. This was based on research showing that sildenafil was not effective
for most women. The maker has commented that women’s sexuality is a complex mix
of physical, emotional, and relationship factors, and it is not as simple to
treat with a medicine as male erectile dysfunction is.11

Currently no medications are approved by the FDA to treat female
sexual problems, although several paths are being studied, including
stimulation of certain molecules (receptors) in the brain and increasing blood
flow to the genitals. It is still too early in the process to know whether any
of these medications will prove to be effective and safe treatment
options.12

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Erection Problems (Erectile Dysfunction) - When To Call a Doctor

Filed under: Uncategorized — waterman9 @ 4:47 am

erectile dysfunction drugs

erection problem (erectile dysfunction) and the
erection lasts longer than 4 hours.

Seek care erectile pill
if you have taken
phosphodiesterase-5 inhibitors (such as Viagra,
Levitra, or Cialis) in the past 24 hours and are having chest pain. Tell your
health professional you are taking this medication. Do
not
use any form of nitroglycerin if you have chest pain and have taken
Viagra, Levitra, or Cialis in the past 24 hours.

Call a health professional if erection problems occur with:

  • Any type of injury to the back, legs, buttocks,
    groin, penis, or testicles.
  • A loss of pubic or armpit hair and an
    enlargement of the breasts.

Make an appointment to see a health professional within 1 to 2
weeks if an erection problem occurs more than 25% of the time and the
problem:

  • Occurs with a persistent
    backache.
  • Occurs after you start taking a new medication or change
    the dose of a medication.
  • Is affecting your self-image or sense of
    well-being.
  • Has not improved despite self-care.

If your erection problem is occasional, there is no reason to call
your health professional. If it occurs frequently but does not bother you or
your partner, you may or may not choose to call your doctor. However, an
erection problem that develops suddenly may be a sign of a disease; it is
dysfunction erectile pill
that you see your doctor.

Watchful Waiting

Watchful waiting is a period of time during which you and your
health professional observe your symptoms or condition without using medical
treatment. A single episode of an erection problem is often a temporary and
easily reversible problem. Do not assume it will happen again. If possible,
forget about it and expect a more successful experience the next time. If you
or your partner is concerned about it, talk about the problem and openly
discuss your fears and anxieties.

If self-care has not helped after 2 weeks and you are concerned
about your inability to have an erection, see a health professional who has
experience in dealing with erection problems.

Who To See

Some health professionals, including doctors and mental health
professionals, may not feel comfortable discussing sexuality and erection
problems. Ask your health professional if he or she feels comfortable with and
has experience in working with men who have erection problems.

The following health professionals can evaluate symptoms of
erection problems:

  • Family medicine
    doctor
  • Internist
  • Nurse
    practitioner
  • Physician assistant
  • Urologist

If it is possible that a psychological problem is contributing to
your erection problem, your doctor may refer you to a health professional such
as a:

To prepare for your appointment, see the topic Making the Most of Your Appointment

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March 17, 2008

Drug May Ease Pulmonary Hypertension

Filed under: Uncategorized — waterman9 @ 5:06 pm

erectile dysfunction drugs

Nov. 16, 2005 — A drug called Revatio may help treat an dysfunction pill
condition called pulmonary arterial hypertension.

Patients with pulmonary hypertension have elevated blood pressure in the pulmonary (lung) blood vessels. The condition often arises from lung problems, but some cases are without a known cause. It can result in heart failure and early death.

Unfortunately, most of the medications that are used to treat this serious condition are not easy to take and are given by IV, injection, or inhalation — with real risks of unwanted side effects.

Revatio has the same active erectile dysfunction pills
— sildenafil — as Viagra. Revatio and Viagra are made by Pfizer.

Pfizer funded the new study, which appears in The New England Journal of Medicine. Pfizer is a WebMD sponsor.

The researchers included Nazzarene Galie, MD, of the cardiology institute at Italy’s Sildenafil citrate tablet of Bologna.

Walking Test

The study lasted for 12 weeks. It included 278 patients with pulmonary hypertension. The patients lived in the U.S., Mexico, South America, Europe, Asia, Australia, South Africa, and Israel.

Three times daily, the patients took Revatio (20, 40, or 80 milligrams) or an empty drug (placebo) orally. That was in addition to any other standard pulmonary hypertension medications.

The big question was how far patients could walk in six minutes. That’s an important exercise test for patients with pulmonary hypertension. The farther patients can walk, the better.

Walking Farther

All of the patients taking Revatio walked farther at the end of the study:

  • 20-milligram group: Walked about 148 extra feet (a 13% increase).
  • 40-milligram group: Walked about 151 extra feet (a 13% increase).
  • 80-milligram group: Walked about 164 extra feet (nearly a 15% increase).

Higher doses didn’t bring a notable increase in distance walked, the researchers report.

Patients were then allowed to take Revatio for up to a year; 230 did so. The researchers looked at the walking tests of 222 of those who were only taking Revatio as treatment. After a year, they walked about 167 extra feet, on average, compared with the beginning of the study.

How Patients Fared

Most of the patients included in the study had milder stages of pulmonary hypertension. Few cases worsened, regardless of treatment type, the study shows.

Patients taking Revatio weren’t any more or less likely to have their symptoms worsen during the trial.

The study wasn’t designed to see if Revatio helped patients live longer. Four died during the study. No deaths were judged to be linked to the treatments, write the researchers.

Side effects seen with Revatio were mild or moderate and included headache, flushing, muscle pain, and diarrhea, report Galie and erectile dysfunction new drugs
.

And some information of erectile problems.

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